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BMB 330: Molecular Genetics
Dr. Peggy Richey
Centre College
For the current BMB 330 syllabus, log on to my BMB 330 Moodle page (login required)
Fall 2009
Lecture Schedule
Text: Weaver.
2008. Molecular Biology. 4th edition. WCB McGraw-Hill. Boston: 894
pgs.
click here to go to
the Student Resources page for the Weaver text. This site contains
animations, diagrams, tutorials and other supplementary information for each
chapter of the book.
Go To: Guidelines and Grading
Click on the links under
"Resources" to review the material and find out more about each
day's topics
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Date
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Class
#
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Topic
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Text
Assignment
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Resources
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8/31
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1
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Introduction/Background
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1: 5-7, 9-11; Ch 2
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Avery
Bio, Avery-3 , History,
Crick,
Franklin, Crick Sampler
, Crick Biography & Papers ,
"We've
discovered the secret of life"
|
|
9/2
|
2
|
Molecular Nature of Genes
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1: 5-7, 9-11; Ch 2
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Molecular
Biology Glossary
A,B,
Z DNA, topoisomerase(1) , nucleotide
quiz (1)
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9/4
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3
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Molecular Cloning Methods
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4
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plasmid cloning
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9/7
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4
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Molecular Cloning Methods
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4
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YAC
cloning
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9/9
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5
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Cloning Methods; Molecular Tools
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4;5: 90-106
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techniques/tools
|
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9/11
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6
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Molecular Tools
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5: 90-106
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PCR
tutorial, techniques/tools
, Sequencing
tutorial
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9/14
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7
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Molecular Tools
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5: 90-106
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|
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9/16
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8
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Molecular Tools
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24: 797-800
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microarrays , microarray tutorial, techniques/tools , microarray
animation (5)
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9/18
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9
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DNA replication
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20: 639-660
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|
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9/21
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10
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Exam I (lectures 1-8)
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|
|
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9/23
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11
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DNA Replication
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20: 639-660
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|
|
9/25
|
12
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DNA Replication
|
21
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Replication
tutorial(5)(click on "DNA Replication),
Pol III B subunit(1)
|
|
9/28
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13
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DNA Replication
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21
|
|
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9/30
|
14
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DNA Replication
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21
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telomeres,
telomere
tutorial(5) (click on "Telomeres"), Lasker Award
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10/2
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15
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DNA Damage and Repair
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20: 660-678
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DNA mutations ,
mutation database
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10/5
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16
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DNA Damage and Repair
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20: 660-678
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DNA repair
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10/7
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17
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Exam II (lectures 9, 11-16)
|
|
|
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10/9
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18
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Prokaryotic transcription
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6:126-154, 159-168
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|
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10/12
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19
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Prokaryotic Transcription
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6:126-154, 159-168
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Transcription tutorial(5)
(click on "Gene Expression")
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10/14
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20
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Prokaryotic Transcription Regulation
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7: 172-188
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lac operon tutorial(5)
(click on Prokaryotic regulation), lac operon quiz , lac operon animation , Jacob and Monod , Nobel
Prize
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10/19
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21
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Prokaryotic Transcription Regulation
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7: 192-196
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attenuation
tutorial
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10/21
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22
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Prokaryotic Transcription Regulation
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8:202-224
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Ptashne's story (you
have to sign in for free access to www.ergito.com),
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10/23
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23
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Prokaryotic Transcription Regulation
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8:202-224
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quiz/tutorial
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10/26
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24
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Eukaryotic Transcription
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10:250-257; 266-276
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RNAPII
structure , central
dogma movie , transcription
animation
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10/28
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25
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Exam III (lectures
18-23)
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|
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10/30
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26
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Eukaryotic Transcription
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11:280-292; 294-306; F11.42
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TFIID
structure , TFIIA/TBP structure(1),
TFIIB/TBP
structure(1)
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11/2
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27
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Eukaryotic Transcription
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12:321-323; 332-340
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DNA
binding motifs , Nobel
Prize
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11/4
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28
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Eukaryotic Transcription
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13: 359-370
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Nucleosome structure(1), Chromosome
structure Structure Tutorial(1) , chromatin tutorial(5)
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11/6
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29
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RNA Processing
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14:399-409; 427-434
F 14.27
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discovery of splicing
(you have to sign in for free access to www.ergito.com),
discovery of snurps , transcription
processing , mRNA
splicing
|
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11/9
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30
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RNA Processing
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15: 444-453
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Splicing Tutorial(2)
(click on "Gene Expression"), ribozymes,
discovery of RNA
catalysis (@www.ergito.com) , plant snoRNAs
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11/11
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31
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RNA Processing
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15: 453-456; 473-476;
16: 481-487
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RNA editing (@www.ergito.com)
, eukaryotic
gene expression quiz
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11/13
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32
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RNA Processing
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16: 481-487; 490
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|
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11/16
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33
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Exam IV (lectures 24, 26-32)
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11/18
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34
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Translation
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19: 607-612; 625-635;
18: 564-573
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ribosome
structure, tRNA structure, genetic
code, summary ,
translation animation
deciphering the
code
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11/20
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35
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Translation
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17:521-547
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|
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11/23
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36
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Translation
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18: 573-574; 577-581
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|
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11/30
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37
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Translation
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18: 583-589; 592-602
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Translation tutorial(2)
(click on "Gene Expression "), EF-Tu/tRNA, RNA is peptidyl transferase (@www.ergito.com)
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12/2
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38
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Translation regulation
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16: 494-509;513-516
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12/4
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39
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Translation regulation
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17: 547-559
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RNAi , Nobel
Prize , RNAi animations
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12/7
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Final Exam 8:30-11:30 a.m. (lectures 34-39)
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(1) requires Chime plug-in--click here to download Chime
(2) requires Shockwave
plug-in--click here
to download Shockwave
(4) requires Shockwave-Authorware plug-in--click
here to download Shockwave-Authorware
(5)
requires Flash player plug-in--click
here to download Flash player
email me: richey@centre.edu
back to Peggy Richey's Home Page
last updated on
July 22, 2010
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