BMB 330: Molecular Genetics
Dr. Peggy Richey
Centre College

 

For the current BMB 330 syllabus, log on to my BMB 330 Moodle page (login required)

Fall 2009
Lecture Schedule


Text: Weaver. 2008. Molecular Biology. 4th edition. WCB McGraw-Hill. Boston: 894 pgs.
click here to go to the Student Resources page for the Weaver text. This site contains animations, diagrams, tutorials and other supplementary information for each chapter of the book. 

Go To: Guidelines and Grading


Click on the links under "Resources" to review the material and find out more about each day's topics

Date

Class #

Topic

Text Assignment

Resources

8/31

1

Introduction/Background

1: 5-7, 9-11; Ch 2

Avery Bio, Avery-3  , History, Crick, Franklin, Crick Sampler , Crick Biography & Papers , "We've discovered the secret of life"

9/2

2

Molecular Nature of Genes

1: 5-7, 9-11; Ch 2

Molecular Biology Glossary
 
A,B, Z DNA, topoisomerase(1) , nucleotide quiz (1)

9/4

3

Molecular Cloning Methods

4

plasmid cloning

9/7

4

Molecular Cloning Methods

4

YAC cloning 

9/9

5

Cloning Methods; Molecular Tools

4;5: 90-106

techniques/tools

9/11

6

Molecular Tools

5: 90-106

PCR tutorial, techniques/tools , Sequencing tutorial  

9/14

7

Molecular Tools

5: 90-106

9/16

8

Molecular Tools

24: 797-800

microarrays  , microarray tutorial, techniques/tools , microarray animation (5)

9/18

9

DNA replication

20: 639-660

 

9/21

10

Exam I (lectures 1-8)

 

9/23

11 

DNA Replication

 20: 639-660

 

9/25

12

DNA Replication

21

Replication tutorial(5)(click on "DNA Replication),
Pol III B subunit(1)

9/28

13

DNA Replication

21

9/30

14

DNA Replication

21

telomeres, telomere tutorial(5) (click on "Telomeres"), Lasker Award

10/2

15

DNA Damage and Repair

20: 660-678

DNA mutations , mutation database

10/5

16

DNA Damage and Repair

20: 660-678

DNA repair

10/7

17

Exam II (lectures 9, 11-16)

 

10/9

18

Prokaryotic transcription

6:126-154, 159-168

10/12

19

Prokaryotic Transcription

6:126-154, 159-168

Transcription tutorial(5) (click on "Gene Expression") 

10/14

20

Prokaryotic Transcription Regulation

7: 172-188

lac operon tutorial(5) (click on Prokaryotic regulation), lac operon quiz   , lac operon animation , Jacob and Monod , Nobel Prize

10/19

21

Prokaryotic Transcription Regulation

7: 192-196

attenuation tutorial

10/21

22

Prokaryotic Transcription Regulation

8:202-224

Ptashne's story (you have to sign in for free access to www.ergito.com),

10/23

23

Prokaryotic Transcription Regulation

 8:202-224

quiz/tutorial

10/26

24

Eukaryotic Transcription

10:250-257; 266-276  

RNAPII structure  , central dogma movie , transcription animation

10/28

25

Exam III (lectures 18-23)

 

 

10/30

26

Eukaryotic Transcription

11:280-292; 294-306; F11.42

TFIID structure  , TFIIA/TBP structure(1),
TFIIB/TBP structure(1)

11/2

27

Eukaryotic Transcription

12:321-323; 332-340

DNA binding motifs  , Nobel Prize

11/4

28

Eukaryotic Transcription

13: 359-370

Nucleosome structure(1), Chromosome structure Structure Tutorial(1) chromatin tutorial(5)  

11/6

29

RNA Processing

14:399-409; 427-434
F 14.27

discovery of splicing (you have to sign in for free access to www.ergito.com), discovery of snurps , transcription processing , mRNA splicing

11/9

30

RNA Processing

15: 444-453

Splicing Tutorial(2) (click on "Gene Expression"), ribozymes, discovery of RNA catalysis (@www.ergito.com) , plant snoRNAs

11/11

31

RNA Processing

15: 453-456; 473-476;

 16: 481-487

RNA editing (@www.ergito.com) , eukaryotic gene expression quiz

11/13

32

RNA Processing

16: 481-487; 490

11/16

33

Exam IV (lectures 24, 26-32)

11/18

34

Translation

19: 607-612; 625-635;     18: 564-573

ribosome structure, tRNA structure, genetic code, summary , translation animation
deciphering the code

11/20

35

Translation

17:521-547

11/23

36

Translation

18: 573-574; 577-581

11/30

37

Translation

18: 583-589; 592-602

Translation tutorial(2) (click on "Gene Expression "), EF-Tu/tRNA, RNA is peptidyl transferase (@www.ergito.com) 

12/2

38

Translation regulation

16: 494-509;513-516

 

12/4

39

Translation regulation

17: 547-559

RNAi , Nobel Prize , RNAi animations

12/7

 

Final Exam 8:30-11:30 a.m. (lectures 34-39)

 

 

(1) requires Chime plug-in--click here to download Chime
(2) requires Shockwave plug-in--click here to download Shockwave
(4) requires Shockwave-Authorware plug-in--click here to download Shockwave-Authorware
(5) requires Flash player plug-in--click here to download Flash player

email me: richey@centre.edu

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last updated on July 22, 2010